Christine Saluzzo

Carte de visite

1:I.U.T LE MANS - Département Chimie, 2:U.F.R SCIENCES et TECHNIQUES - IMMM-Institut des Molécules et Matériaux du Mans

Mobile : (33) (0)2 43 83 33 37

Fax : (33) (0)2 43 83 39 02

Adresse : DEPARTEMENT METHODOLOGIE DE SYNTHESE
INSTITUT DES MOLECULES MATERIAUX DU MANS
FACULTÉ DES SCIENCES
Unité Mixte de Recherche CNRS 6283
Av. O. Messiaen
72085 Le Mans Cedex 9
France

Description

Thèmes de recherche

     Catalyse asymétrique – Organocatalyse asymétrique

     Synthèse multi-étape de composés à activité biologique

Parcours

1989 - Doctorat de Chimie organique - Université Claude Bernard Lyon I (Pr. André Laurent)

1990 - Recherche Post doctorale - Texas A & M University, College Station, Texas (USA). (Pr. Dereck H. R. Barton)

1990 - 2002 - Maître de conférences - Université Claude Bernard Lyon I

1999 - Habilitation à Diriger des Recherches – Université Claude Bernard Lyon I

Depuis 2002 - Professeur des Universités - Université du Maine - IUT du Mans

Activité

Recherche

Articles

Formal addition of methanesulfenyl fluoride to unsaturated substrates” Haufe, Gunter ; Alvernhe, Gerard ; Anker, Daniel ; Laurent, Andre ; Saluzzo, Christine Tetrahedron Letters (1988), 29(19), 2311-14.

“Phenylselenofluorination of alkynes” Saluzzo, Christine ; Alvernhe, Gerard ; Anker, Daniel ; Haufe, Gunter Tetrahedron Letters (1990), 31(15), 2127-30.

Synthesis of β -fluoroalkyl phenyl (or methyl) thioethers by sulfur-assisted halogen exchange with triethylamine tris(hydrofluoride)” Saluzzo, Christine ; Alvernhe, Gérard ; Anker, Daniel ; Haufe, Gunter. Journal of Fluorine Chemistry (1990), 47(3), 467-79.

Phenylselenofluorination of acid-sensitive alkenes” Saluzzo, Christine ; Alvernhe, Gerard ; Anker, Daniel ; Haufe, Gunter Tetrahedron Letters (1990), 31(5), 663-6.

“Phenylsélénofluoration d’alcynes” Saluzzo, Christine ; Anker, Daniel ; Alvernhe, Gérard ; Haufe, Gunter. Journal of Fluorine Chemistry (1990), 45(1), 148.

“Synthesis of fluoroalkyl methyl thioethers by formal addition of methanesulfenyl fluoride to alkenes” Haufe, Gunter ; Alvernhe, Gerard ; Anker, Daniel ; Laurent, Andre ; Saluzzo, Christine Journal of Organic Chemistry (1992), 57(2), 714-19.

“Stereocontrolled formation of functionalized erythro-1,2-diols via hydroboration of 2-alkyl-4,5-dihydrofurans” Amouroux, Roger ; Slassi, Abdelmalik ; Saluzzo, Christine Heterocycles (1993), 36(9), 1965-9.

“Phenylthio (and phenylseleno)fluorination of alkenes and alkynes using N-phenylthio (and phenylseleno)phthalimide combined with pyridine•9HF or Et3N•3HF complexes” Saluzzo, Christine ; La Spina, Anna-Maria ; Picq, Dominique ; Alvernhe, Gerard ; Anker, Daniel ; Wolf, Dieter ; Haufe, Gunter Bulletin de la Société Chimique de France (1994), 131(8), 831-

“Regiocontrolled ring opening of 2-methyltetrahydrofuran with acid chlorides and iodides” Mimero, Pascal ; Saluzzo, Christine ; Amouroux, Roger Tetrahedron Letters (1994), 35(10), 1553-6.

“Regioselective cleavage of tetrahydrofurans bearing proximate functional groups with acid iodides” Mimero, Pascal ; Saluzzo, Christine ; Amouroux, Roger Synthetic Communications (1995), 25(5), 613-27.

“A direct single ring cleavage of isosorbide and isomannide with iodotrimethylsilane” Ejjiyar, Soumeya ; Saluzzo, Christine ; Amouroux, Roger ; Massoui, Mohamed Tetrahedron Letters (1997), 38(9), 1575-1576.

“Isosorbide and isomannide synthons : novel chiral amphiphilic molecules” Ejjiyar, Soumeya ; Massoui, Mohammed ; Saluzzo, Christine ; Amouroux, Roger ; Colman, Anthony W. Comunicaciones presentadas a la Jornadas del Comite Espanol de la Detergencia (1999), 29, 511-520.

“Grignard reagent/borohydride combinations. Alkylation/reduction of esters” Hallouis, Sophie ; Saluzzo, Christine ; Amouroux, Roger Synthetic Communications (2000), 30(2), 313-324.

“O4,O5-isopropylidene-1,2:3,6-dianhydro-D-glucitol from isosorbide” Ejjiyar, Soumeya ; Saluzzo, Christine ; Amouroux, Roger Organic Syntheses (2000), 77, 91-97.

“Recent progress in asymmetric heterogeneous catalysis : use of polymer-supported catalysts” Saluzzo, Christine ; ter Halle, Rob ; Touchard, François ; Fache, Fabienne ; Schulz, Emmanuelle ; Lemaire, Marc Journal of Organometallic Chemistry (2000), 603(1), 30-39.

Synthesis and assembly properties of a series of chiral amphiphilic dihydroxytetrahydrofuran derivatives” Ejjiyar, Soumeya ; Saluzzo, Christine ; Massoui, Mohammed ; Amouroux, Roger ; Terry, Nicolas ; Coleman, Anthony W. Journal of Physical Organic Chemistry (2001), 14(1), 1-10.

Grignard cross-coupling catalyzed by chiral phosphino-quincorine and phosphino-quincoridine derivatives” Pellet-Rostaing, Stéphane ; Saluzzo, Christine ; Ter Halle, Rob ; Breuzard, Jérémy ; Vial, Laurent ; Le Guyader, Frédéric ; Lemaire, Marc Tetrahedron : Asymmetry (2001), 12(14), 1983-1985.

Enantiopure poly(glycidyl methacrylate-co-ethylene glycol dimethacrylate) : a new material for supported catalytic asymmetric hydrogen transfer reduction” Rolland, Alice ; Herault, Damien ; Touchard, François ; Saluzzo, Christine ; Duval, Raphael ; Lemaire, Marc Tetrahedron : Asymmetry (2001), 12(5), 811-815.

“Hydrogenation of ethyl acetoacetate catalyzed by hydrosoluble BINAP derivatives” Lamouille, Thierry ; Saluzzo, Christine ; ter Halle, Rob ; Le Guyader, Frédéric ; Lemaire, Marc Tetrahedron Letters (2001), 42(4), 663-664.

“Homogeneous-supported catalysts for enantioselective hydrogenation and hydrogen transfer reduction” Saluzzo, Christine ; Lemaire, Marc Advanced Synthesis & Catalysis (2002), 344(9), 915-928.

“Synthesis of a new water-soluble C2-symmetric chiral diamine : preliminary investigation of its catalytic properties for asymmetric hydrogenation under biphasic conditions” Maillet, Celine ; Praveen, Thoniyot ; Janvier, Pascal ; Minguet, Sebastien ; Evain, Michel ; Saluzzo, Christine ; Tommasino, M. Lorraine ; Bujoli, Bruno Journal of Organic Chemistry (2002), 67(23), 8191-8196.

“Synthesis and studies of 6,6’-BINAP derivatives for the heterogeneous asymmetric hydrogenation of methyl acetoacetate” Saluzzo, Christine ; Lamouille, Thierry ; Le Guyader, Frédéric ; Lemaire, Marc Tetrahedron : Asymmetry (2002), 13(11), 1141-1146.

“Polymer-Supported catalysts : Enantioselective hydrogenation and hydrogen transfer reduction” Saluzzo, Christine ; Lamouille, Thierry ; Herault, Damien ; Lemaire, Marc
Bioorganic & Medicinal Chemistry Letters (2002), 12(14), 1841-1844.

Enantiopure beads : a tool for asymmetric heterogeneous catalysis” Herault, Damien ; Saluzzo, Christine ; Duval, Raphael ; Lemaire, Marc. Journal of Molecular Catalysis A : Chemical (2002), 182-183, 249-256.

“New P,N ligands with chiral nitrogen center : applications in homogeneous catalysis.” Saluzzo, Christine ; Breuzard, Jeremy ; Pellet-Rostaing, Stephane ; Vallet, Martial ; Le Guyader, Frédéric ; Lemaire, Marc Journal of Organometallic Chemistry (2002), 643-644, 98-104.

4,4’ and 5,5’-DiamBINAP as a hydrosoluble chiral ligand : syntheses and use in Ru(II) asymmetric biphasic catalytic hydrogenation.” Berthod, Mikael ; Saluzzo, Christine ; Mignani, Gerard ; Lemaire, Marc Tetrahedron : Asymmetry (2004), 15(4), 639-645.

“Chiral polyamino alcohols and polyamino thiols for asymmetric heterogeneous catalysis.” Herault, Damien ; Saluzzo, Christine ; Lemaire, Marc Tetrahedron : Asymmetry (2006), 17(13), 1944-1951.

Preparation of monodisperse enantiomerically pure glycidyl methacrylate-ethylene glycol dimethacrylate copolymers in dispersion copolymerization : Functionalization.” Herault, Damien ; Saluzzo, Christine ; Lemaire, Marc Reactive & Functional Polymers (2006), 66(5), 567-577.

Total synthesis of a novel macrotetrolide.”Coutable, Ludovic ; Adil, Karim ; Saluzzo, Christine Tetrahedron (2008), 64(49), 11296-11303.

“A general and highly efficient synthesis of novel nonactic acid analogues.” Coutable, Ludovic ; Saluzzo, Christine Synthesis (2008), (21), 3389-3396.

“New chiral ligands from isosorbide : application in asymmetric transfer hydrogenation.” Guillarme, Stephane ; Nguyen, Thi Xuan Mai ; Saluzzo, Christine Tetrahedron : Asymmetry (2008), 19(12), 1450-1454.

“Synthesis and glycosidase inhibitory activity of 1-amino-3,6-anhydro-1-deoxy-D-sorbitol derivatives” Guillarme, Stephane ; Behr, Jean-Bernard ; Bello, Claudia ; Vogel, Pierre ; Saluzzo, Christine Bioorganic Chemistry (2010), 38(2), 43-47.

“New class of beta-aminoalcohol ligands derived from isosorbide and isomannide : application in hydrogen transfer reduction of prochiral ketones.” Le Thin, Thanh ; Guillarme, Stéphane ; Saluzzo, Christine Tetrahedron (2010), 66(46), 8893-8898. DOI : 10.1016/j.tet.2010.09.060

Nitrogen-Containing Ligands Anchored onto Polymers as Catalyst Stabilizer for Catalytic Enantioselective Reactions” Saluzzo Christine, Guillarme Stéphane Advances in Chemistry Research, (2010) 3 257-388.

“A convergent hetero Diels-Alder strategy for asymmetric access to a lactone containing two lipidic chains” Vu, Cong Sau ; Guisot, Nicolas ; Guillarme, Stephane ; Martel Arnaud; Dujardin, Gilles ; Pipelier, Muriel ; Dubreuil, Didier ; Saluzzo, Christine. European Journal of Organic Chemistry (2012) 2012 (20) 3727-3731, S3727/1-S3727/49.

“3-Fluoro- and 3,3-difluoro-3,4-dideoxy-KRN 7000 analogues as new potent immunostimulator agents: total synthesis and biological evaluation in huiman invariant natural killer T cells and mice” Hunaud, Julie ; Diswal, Mette ; Frison, Jean Cedric ; Blot, Virginie ; Rocher, Jezabel ; Marionneau-Lambot, Severine ; Ouillier, Thibauld ; Douillard, Jean-Yves ; Guillarme, Stéphane ; Saluzzo, Christine ; Dujardin, Gilles ; Jacquemin, Denis ; Graton, Jérôme ; Le Questel, Jean-Yves ; Evain, Michel ; Lebreton, Jacques ; Dubreuil, Didier ; Le Pendu Jacques ; Pipelier, Muriel. Journal of Medicinal Chemistry (2012), 55(3), 1227-1241.

Dianhydrohexitols: new tools for organocatalysis. Application in enantioselective Friedel Crafts alkylation of indoles with nitroalkenes Chen, Ling-Yan ; Guillarme, Stéphane ; Saluzzo Christine. Arkivoc, (2013), (iii) 227-244. 

"Asymmetric Michael addition of acetone to  β-nitrostyrenes catalyzed by novel organocatalysts derived from D-isomannide or L-isoidide"  Chen, Ling-Yan ; Guillarme, Stéphane ; Whiting Andrew ; Saluzzo Christine. Arkivoc, (2014), (iv) 215-227.

Isohexides as versatile scaffolds for asymmetric catalysis” ; Kadraoui Mohammed, Maunoury Thibault, Derriche Zoubir, Guillarme Stéphane, Saluzzo Christine. Eur. J. Org.Chem., (2015), 441-457.

 

 

Brevets

Optically active linear polymer used as ligand in the preparation of metallic complexes designed for asymmetric catalysis Lemaire, Marc ; Ter Halle, Rob ; Schulz, Emmanuelle ; Colasson, Benoit ; Spagnol, Michel ; Saluzzo, Christine ; Lamouille, Thierry PCT Int. Appl. (2000), WO 2000052081 A1 20000908

Preparation of chiral ( β -aminoalkyl)phosphines, -phosphites, -phosphonites, and -phosphinites and use of their platinum-group metal complexes in asymmetric catalysis Lemaire, Marc ; Pellet Rostaing, Stephane ; Breuzard, Jeremy ; Ter Halle, Rod ; Saluzzo, Christine ; Vallet, Martial Fr. Demande (2001), FR 2810666 A1 20011228.

Water-soluble chiral diphosphines for catalysis of asymmetric hydrogenations by Group VIII-metal complexes Saluzzo, Christine ; Lamouille, Thierry ; Lemaire, Marc ; Ter Halle, Rob PCT Int. Appl. (2001), WO 2001074828 A1 20011011.

Optically active polymer with epoxide functions, method for preparing same, and use thereof Lemaire, Marc ; Saluzzo, Christine ; Rolland, Alice ; Touchard, Francois ; Herault, Damien PCT Int. Appl. (2002), WO 2002042346 A1 20020530.

Chiral 4,4’-disubstituted binaphthyl diphosphines, their preparation, and their uses as ligands in asymmetric hydrogenation catalysts Lemaire, Marc ; Saluzzo, Christine ; Berthod, Mikael Fr. Demande (2004), FR 2849037 A1 20040625.

Chiral 5,5’-disubstituted binaphthyl diphosphines, processes for their preparation, and their uses as ligands in asymmetric hydrogenation catalysts Lemaire, Marc ; Saluzzo, Christine ; Berthod, Mikael Fr. Demande (2004), FR 2849036 A1 20040625.

Water-soluble chiral diphosphines and their uses as ligands on transition-metal catalysts for asymmetric synthesis Lemaire, Marc ; Saluzzo, Christine ; Berthod, Mikael Fr. Demande (2004), FR 2853652 A1 20041015.

Diphosphines, preparation and uses thereof for manufacture of ligands for metal complex catalysts Lemaire, Marc ; Saluzzo, Christine ; Berthod, Mikael PCT Int. Appl. (2004), WO 2004056483 A1 20040708.

New C-Glycosides and their applications as anti-cancer, anti-diabetic agents and substrates for storage disorder diseases Guisot, Nicolas ; Guillarme, Stephane ; Saluzzo, Christine ; Dujardin, Gilles ; Dubreuil, Didier ; Demande FR 12 58165 ( 31/08/2012) (annulé)

Ouvrages – Chapitres de livre

Saluzzo Christine, Guillarme Stéphane “Nitrogen-Containing Ligands Anchored onto Polymers as Catalyst Stabilizer for Catalytic Enantioselective Reactions” (chap.3) in Polymer Aging, Stabilizers and Amphiphilic Polymer Block Copolymers" Editions Novapublisher, Edts L. Segewicz et M. Petrowsky (128 pages), 2011 (ISBN : 978-1-60692-928-5). e-book 2011 (ISBN : 978-1-61470-600-7).

Saluzzo Christine, Guillarme Stéphane “Encyclopedia of Polymer Research” (chap.3) p. 45-172. Editions Novapublisher, Edt Caroline E. Jones, 2011 (ISBN : 978-1-61761-926-7). e-book 2011 (ISBN : 978-1-61122-209-8).

Saluzzo Christine, Guillarme Stéphane “Nitrogen-Containing Ligands Anchored onto Polymers as Catalyst Stabilizer for Catalytic Enantioselective Reactions”  in Chemistry Research Summaries, Vol 1,   Editions Novapublisher, Edts E. S. Hüseynov, V. Babayer, E. S. Hüseynov, V. Babayer, 2012 (ISBN : 978-1-61668-680-2).

Saluzzo Christine, Guillarme Stéphane “Nitrogen-Containing Ligands Anchored onto Polymers as Catalyst Stabilizer for Catalytic Enantioselective Reactions” in Chemistry research summary (vol 1) Editions Novapublisher, 2012 (ISBN : 978-1-62257-633-3).

Livres

Saluzzo Christine, Guillarme Stéphane Asymmetric Heterogeneous Supported Catalysis : Uses of Nitrogen Containing Ligands, Editions Novapublisher, 1ère édition 2010 (ISBN : 978-1-61728-101-3). 2eme édition 2012 (ISBN : 978-1-61668-680-2). e-book 2012 (ISBN : 978-1-61728-101-3).

 

Enseignement

Ouvrages

100 Manipulations de Chimie Organique et de Chimie Inorganique Editions Bréal
Mesplède, Jacques ; Saluzzo, Christine

1ère édition, 2002 ( ISBN : 2-7495-0060-7)

2ème édition, 2004 (ISBN : 2-7495-0352-3)