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Innovative heterobifunctional azlactone-based linkers

Innovative heterobifunctional azlactone-based linkers

Azlactone-based heterobifunctional linkers that proceed in orthogonal click-like reactions for chemical ligations in biologically relevant medium without releasing any by-product.

 

Researchers

  • Sagrario Pascual
  • Véronique Montembault
  • Laurent Fontaine

Related papers

  • Fontaine, H. T. Ho, S. Pascual, V. Montembault, PCT WO2014060357; US 20150285811A1; Japanese Patent n° 6262746 (2017)
  • T. Ho, A. Bénard, G. Forcher, M. Le Bohec, V. Montembault, S. Pascual, L. Fontaine, Org. Biomol. Chem. 2018, 16, 7124-7128.
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