Click chemistry for functional polymers

Functional norbornenyl-based macromonomers and RAFT-synthesized thermosensitive polymers have been synthesized by CuAAC and controlled polymerizations (ROP and RAFT). Thermo-activated and photo-activated hydrothiolations including thiol-ene and thiol-yne perfomed on such macromonomers and polymers have been monitored to target well-defined mikto-arm polymers and telechelic polymers in one-pot processes. Decorated iron magnetic nanoparticles with functional hydrophile ligands leading to core-shell nanoparticles have been employed to target hybrid nanoparticles for hyperthermia drug release and reversible magneto-sensitive hydrogels via Diels-Alder reactions.

  Researchers

• Véronique Montembault
• Sandie Piogé
• Sagrario Pascual
• Laurent Fontaine
• Florent Calvayrac
• Lazhar Benyahia

Related papers

• T. T. N'Guyen, K. Oussadi, V. Montembault, L. Fontaine, J. Polym. Sci., A: Polym. Chem. 2013, 51, 415-423.
• T. T. N’Guyen, H. T. T. Duong, J. Basuki, V. Montembault, S. Pascual, C. Guibert, J. Fresnais, C. Boyer, M. R. Whittaker, T. P. Davis, L. Fontaine, Angew. Chem. Int. Ed. 2013, 52, 14152-14156
• Cabanetos, W. Bentoumi, E. Blart, Y. Pellegrin, V. Montembault, Y. Bretonnière, C. Andraud, L. Mager, L. Fontaine, F. Odobel, Polym. Adv. Technol. 2013, 24, 473-477.
• T. T. N’Guyen, G. Contrel, V. Montembault, G. Dujardin, L. Fontaine, Polym. Chem.2015, 6, 3024-3030
• Feng, F. Calvayrac, V. Montembault, L. Fontaine, J. Phys.: Conf. Series 2015, 633, 012003/1-012003/8.
• D. A. N'Guyen, V. Montembault, S. Piogé, S. Pascual, L. Fontaine, J. Polym. Sci. Part A: Polym. Chem. 2017, 55, 4051-4061. (DOI: 10.1002/pola.20170550).
• M. Le Bohec, S. Piogé, S. Pascual, L. Fontaine, J. Polym. Sci. Part A: Polym. Chem. 2017, 55, 3597-3306. (DOI: 10.1002/pola.28742).
• Gharbi, F. Salles, P. Mathieu, C. Amiens, V. Collière, Y. Coppel, K. Philippot, L. Fontaine, V. Montembault, L. S. Smiri, D. Ciuculescu-Pradines, New J. Chem. 2017, 41, 11898
• Blin, A Niederberger, L. Benyahia, J. Fresnais, V. Montembault, L. Fontaine, Polym. Chem. 2018, DOI :10.1039/c8py01006d