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Hyperthermia-sensitive hybrid nanoparticles and magneto-sensitive hydrogels

Hyperthermia-sensitive hybrid nanoparticules and magneto-sensitive hydrogels

Magnetic hybrid nanoparticles have been obtained from iron oxide nanoparticles (IONPs) and (di)furan-functionalized (di)phosphonic acid-terminated poly(ethylene oxide)s. The reversibility of the Diels-Alder reaction between the furan functionality(ies) and maleimide derivatives has been used to design hyperthermia-sensitive hybrid nanoparticles and thermo-sensitive double-crosslinked networks using magnetic iron oxide nanoparticles as crossing points, making these materials potential candidates for new applications mediated by magnetic hyperthermia stimuli, a key requirement for long-term medical therapy.



  • Véronique Montembault
  • Sagrario Pascual
  • Lazhar Benyahia
  • Florent Calvayrac
  • Laurent Fontaine

Related papers

  • T. T. N'Guyen, K. Oussadi, V. Montembault, L. Fontaine, J. Polym. Sci., A: Polym. Chem. 2013, 51, 415-423.
  • T. T. N’Guyen, H. T. T. Duong, J. Basuki, V. Montembault, S. Pascual, C. Guibert, J. Fresnais, C. Boyer, M. R. Whittaker, T. P. Davis, L. Fontaine, Angew. Chem. Int. Ed. 2013, 52, 14152-14156.
  • T. T. N’Guyen, G. Contrel, V. Montembault, G. Dujardin, L. Fontaine, Polym. Chem.20156, 3024-3030.
  • Feng, F. Calvayrac, V. Montembault, L. Fontaine, J. Phys.: Conf. Series 2015, 633, 012003/1-012003/8.
  • Gharbi, F. Salles, P. Mathieu, C. Amiens, V. Collière, Y. Coppel, K. Philippot, L. Fontaine, V. Montembault, L. S. Smiri, D. Ciuculescu-Pradines, New J. Chem., 2017, 41, 11898.
  • Blin, A. Niederberger, L. Benyahia, J. Fresnais, V. Montembault, L. Fontaine Polym. Chem. 2018, 9, 4642-4650.
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