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Innovative hetero-functional monomer: Vinylazlatone

Innovative hetero-functional monomer: Vinylazlatone

Azlactone-derived polymers synthesized by controlled RAFT polymerization are able to react with amines according to the “click” chemistry concept: with full atom economy, quantitatively and with total chemoselectivity. Such feature leads to thermosensitive lysozyme bioconjugates, thermosensitive metallo-supramolecular flower-like micelles and antibody-functionalized magnetic nanoparticles.



  • Sagrario Pascual
  • Sandie Piogé
  • Véronique Montembault
  • Lazhar Benyahia
  • Laurent Fontaine

Related papers

  • T.H. Ho, M.E. Levere, S. Pascual, V. Montembault, N. Casse, A. Caruso, L. Fontaine, Polym. Chem. 2013, 4, 675-685
  • Delplace, S. Harrisson, H. T. Ho, J. A. Tardy, Y. Guillaneuf, S. Pascual, L. Fontaine, J. Nicolas, Macromolecules 2015, 48, 2087-2097
  • Pray-In, C. Boonthip, B. Rutnakornpituk, U. Wichai, V. Montembault, S. Pascual, L. Fontaine, M. Rutnakornpituk, Materials Science & Engineering, C: Materials for Biological Applications 2016, 67, 285-293
  • M. Le Bohec, M. Banère, S. Piogé, S. Pascual, L. Benyahia, L. Fontaine, Polym. Chem. 2016, 7, 6834
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